Our mission is to identify new therapies for vascular disease that target the cells of the blood vessel wall. Vascular diseases such as coronary artery disease, stroke, and peripheral artery disease remain the leading causes of death in the United States and throughout the world. Despite this, we have no therapies that target the cells of the blood vessel wall where the disease begins. Our lab applies the latest techniques in human genetics, genomics, and single cell analysis to identify new mechanistic pathways. We work in the Divisions of Cardiology and Genetics at Brigham and Women’s Hospital and the Medical and Population Genetics Group at the Broad Institute.